Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors

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Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors

In Saccharomyces cerevisiae, peroxisomal inheritance from mother cell to bud is conducted by the class V myosin motor, Myo2p. However, homologues of S. cerevisiae Myo2p peroxisomal receptor, Inp2p, are not readily identifiable outside the Saccharomycetaceae family. Here, we demonstrate an unexpected role for Pex3 proteins in peroxisome inheritance. Both Pex3p and Pex3Bp are peroxisomal integral...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2009

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.200902117